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Dear colleague,



You are invited to participate in a protein and large molecule drug development survey. It will take approximately 5 minutes to complete the questionnaire.


Your participation in this study is completely voluntary. If you feel uncomfortable answering any questions, you can withdraw from the survey at any point. If you wish to register for the iPod giveaway, you may do so at the end of the survey. Again, this is optional. It is very important for us to learn your opinions.


Your survey responses will be stricly confidential. If you have questions at any time about the survey or the procedures, you may contact BioProtfolio at Tel: +44 1300 321501 or + 1 415 680 2472 or by email at [email protected]


Thank you very much for your time and support. Please start with the survey now by clicking on the Continue button below.
 
 

My company produces protein therapeutics as: (check all that apply)
 
lyophilized powders
 
frozen solutions
 
ambient solutions
 
Other
 

 
 

My company develops the following (check all that apply):
 
drug delivery devices
 
mucopolysaccharide therapeutics
 
protein therapeutics
 
glycoprotein therapeutics
 
nucleic acid therapeutics
 
peptidoglycan therapeutics
 
small molecule therapeutics
 
Other
 
 
vaccines

 
 

I or my institution, outsource the following protein therapeutic projects:



 
Only the routine sample analysis projects
 
Very little, we do most internally
 
Only the problem projects
 
Everything
 
Never, we do everything inside
 
Other
 

 
 

In terms of characterizing protein therapeutics, which techniques do you feel are most important for developing an understanding of the molecule? (Please rank techniques with 1 being most important, 5 being least important)
Mass Spectrometry (LC/MS, MS/MS, MALDI-TOF)
Hydrodynamic (Dynamic Light Scattering, SEC)
Optical (Flouresence, UV/VIS)
Electrophoretic (SDS PAGE, IEF)
Thermal (DSC, TGA, ITC)
Spectroscopic (Raman, CD, NMR)
Chromatographic (HPLC, FPLC)
 
 

I or my institution currently conduct internally the following studies when developing a protein or large molecule therapeutic (check all that apply):
 
Purity Assays
 
Related Substance Assays
 
Formulation Screening/Excipient Compatibility
 
Stability Assays
 
Endotoxin Assays
 
Creation of a Well-Characterized Reference Standard
 
Characterization
 
Other
 

 
 

If lyophilized powder or crystalline material is produced during the production of your protein, are there assays performed in the solid state? (check those that are appropriate)
 
Not Applicable
 
Yes, X-ray Diffraction
 
Yes, FT-IR
 
Yes, Raman
 
Yes, Other technique:
 

 
 

I or my institution currently outsource the following when developing a protein or large molecule therapeutic (check all that apply):
 
Endotoxin Assays
 
Purity Assays
 
Characterization
 
Excipient Compatibility
 
Stability Assays
 
Related Substance Assays
 
Formulation Screening

 
 

In my opinion, the following services need to be developed with respect to protein or large molecule therapeutics:(Please rank with 1 being most improtant, 5 being least important)
Structural Characterization Services
Stability Analysis
Related Substance Analysis
Immunogenicity Screening
Regulatory Submission Support
Stabilizer Development
 
 

Our annual budget for protein-related services is approximately:
 
$0
 
<$100,000
 
$100,000-$250,000
 
$250,000-$750,000
 
>$750,000
 
Other
 
 
 
 
In my opinion, the biggest issue with protein therapeutic development is (or will be):
   
 
 

I routinely read the folowing journals: (check all that apply)
 
Drug Discovery Today
 
Other
 
 
ProteoMonitor
 
Drug Discovery and Development
 
Proteomics & Genomics
 
Genetic Engineering News
 
Nature Biotechnology
 
Science
 
Biotechniques
 
Modern Drug Discovery

 
 
 
I'd like to be registered for the iPod drawing. (Please include your name, phone, and email below). Your information will not be sold or distributed by the survey sponsor. If you do not wish to be registered in the drawing, please leave this question blank.
   
 
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